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. 2020 Jul 24;10:12391. doi: 10.1038/s41598-020-68837-y

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Spike Density Function. (a-c) Averaged firing rate profiles for each condition as normalized spike-density function (light colors for control and bright color for MK801 group), and their respective differences (white dotted lines). Solid horizontal white lines represent the time in which the difference between groups is significant (two-sample t test p < 0.05, Bonferroni corrected). (d-f) Indices over time computed for 12 intervals (from -50 to 190ms) compared against zero (signed-rank test and FDR corrected for 12 comparisons; *p < 0.01) for each group (light colors for control and bright color for MK801 group). Solid white lines denote differences between groups across time intervals (two-sample t test for each of the 12-time windows, p < 0.05).