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. 2020 Jul 24;10:12436. doi: 10.1038/s41598-020-69427-8

Table 2.

Regression model of different chronological forms of anxiousness, sociodemographic as well as cardiovascular risk factors and distress on onset CVD for total sample, men and women.

Variables Total sample Men Women
OR 95% CI p-value OR 95% CI p-value OR 95% CI p-value
Form of anxiousness
Previous vs never 1.204 0.89–1.61 0.22 1.183 0.78–1.74 0.41 1.185 0.75–1.83 0.45
New onset vs never 1.471 1.05–2.03 0.021 1.344 0.84–2.06 0.19 1.682 1.00–2.72 0.041
Chronic vs never 1.794 1.29–2.46 0.00038 2.353 1.52–3.57 < 0.0001 1.340 0.81–2.17 0.25
Sociodemographics
Sex 1.802 1.46–2.24 < 0.0001
Age (10 years) 1.884 1.67–2.12 < 0.0001 2.011 1.74–2.34 < 0.0001 1.642 1.34–2.02 < 0.0001
Socioeconomic status 0.979 0.96–1.00 0.092 1.000 0.98–1.03 0.99 0.932 0.89–0.97 0.0019
Cardiovascular risk
Diabetes 1.294 0.99–1.68 0.057 1.405 1.01–2.05 0.015 0.975 0.59–1.55 0.92
Obesity 1.436 1.15–1.78 0.0010 1.448 1.10–1.91 0.0079 1.339 0.94–1.89 0.10
Smoking 1.053 0.77–1.42 0.74 0.998 0.65–1.43 0.91 1.139 0.67–1.85 0.62
Hypertension 1.664 1.30–2.14 < 0.0001 1.289 0.94–1.72 0.13 2.748 1.79–4.34 < 0.0001
Dyslipidemia 2.747 2.24–3.38 < 0.0001 3.287 2.44–4.17 < 0.0001 2.173 1.55–3.04 < 0.0001
FH of MI/Stroke 1.034 0.82–1.30 0.78 0.861 0.58–1.12 0.22 1.363 0.96–1.91 0.076
Distress
Social phobia 1.150 0.69–1.84 0.58 0.754 0.31–1.56 0.46 1.663 0.85–3.02 0.11
Panic 1.634 1.07–2.45 0.020 1.448 0.82–2.67 0.17 1.911 1.03–3.40 0.033
Sleep disturbance 1.038 0.75–1.42 0.82 1.302 0.84–1.93 0.23 0.764 0.45–1.24 0.30

OR, Odds ratio; 95% CI, 95% confidence interval; sex 1 = male, 0 = female; cardiovascular risk and distress: 0 = does not apply, 1 = applies; FH of MI/Stroke, Family History of Myocardial infarction/Stroke; Cardiovascular disease events: Total sample: 443 (out of 9,488); Men: 279 (out of 4,780); Women: 164 (out of 4,708).