Table 3.
Regression model of different chronological forms of anxiousness, sociodemographic factors, cardiovascular risk factors and distress on all-cause mortality.
| Variables | HR | 95% CI | p-value | c-index |
|---|---|---|---|---|
| Anxiousness | ||||
| previous vs never | 1.1886 | 0.83–1.70 | 0.35 | 0.00001 |
| new onset vs never | 1.1629 | 0.75–1.81 | 0.50 | 0.00028 |
| chronic vs never | 1.2362 | 0.78–1.97 | 0.37 | 0.00008 |
| Sociodemographics | ||||
| Sex | 2.2717 | 1.70–3.04 | < 0.0001 | 0.01111 |
| Age (10 years) | 3.3669 | 2.80–4.04 | < 0.0001 | 0.11301 |
| Socioeconomic status | 0.9862 | 0.96–1.02 | 0.37 | 0.00040 |
| Cardiovascular risk | ||||
| Diabetes | 2.2314 | 1.67–2.98 | < 0.0001 | 0.00692 |
| Obesity | 1.2870 | 0.98–1.70 | 0.074 | − 0.00005 |
| Smoking | 1.9254 | 1.32–2.80 | 0.00062 | 0.00607 |
| Hypertension, | 0.7700 | 0.58–1.03 | 0.078 | 0.00101 |
| Dyslipidemia, | 1.0014 | 0.77–1.30 | 0.99 | − 0.00009 |
| FH of MI/Stroke | 1.3132 | 0.99–1.74 | 0.059 | 0.00189 |
| Distress | ||||
| Social phobia | 1.4217 | 0.75–2.70 | 0.28 | 0.00217 |
| Panic | 1.1768 | 0.61–2.25 | 0.62 | 0.00192 |
| Sleep disturbance | 1.2782 | 0.87–1.88 | 0.21 | 0.00325 |
OR, Odds ratio; 95% CI, 95% confidence interval; sex 1 = male, 0 = female; cardiovascular risk and distress: 0 = does not apply, 1 = applies; FH of MI/Stroke = Family History of Myocardial infarction/Stroke; Death events: 246 (out of 10,566). The C-index is a concordance statistic which considers the censored observation time in time to event data.