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. 2020 Jul 24;10:12422. doi: 10.1038/s41598-020-69068-x

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Transmission electron microscope images of sections of saline (control) and PAMAM-CNT-dsRNA_αtub exposed T. castaneum larvae. Representative sections proximal to midgut tissue are shown. Arrows highlight intracellular vesicles containing PAMAM-CNT aggregates. Labels are rough endoplasmic reticulum (Rer), septate junction (Sj), mitochondria (M), microvilli (Mv) and nucleus (N) Scale = 2 µm.