Table 2.
Effect of APOE ɛ4 and the two polygenic scores on cognitive performance (cog-comp).
| T1–T5 | Estimate | SE | t | p | ||
|---|---|---|---|---|---|---|
| APOE ɛ4 | −1.198e − 02 | 5.167e − 02 | −0.232 | 0.816708 | ||
| PGS-COG | 1.697e − 01 | 2.310e − 02 | 7.346 | 3.82e−13 | *** | |
| PRS-LOAD | −1.915e − 02 | 2.320e − 02 | −0.825 | 0.409343 | ||
| Time*APOE ɛ4 | −2.985e − 03 | 1.932e − 03 | −1.545 | 0.122389 | ||
| Time*PGS-COG | −9.061e − 04 | 9.045e − 04 | −1.002 | 0.316550 | ||
| Time*PRS-LOAD | −1.985e − 03 | 8.739e − 04 | −2.271 | 0.023207 | * |
Effect of APOE ɛ4 and the two polygenic scores on cognitive performance (cog-comp), estimated based on cognitive tests performed up until T5, when participants were subsequently confirmed to have stayed non-demented for at least 6 years. n = 1081 participants. *p = <0.05, **p = <0.01, ***p = 0.001. All p’s are reported at an uncorrected level.
Bold values indicates significant variables.