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. 2020 Jul 24;11(7):573. doi: 10.1038/s41419-020-02749-7

Fig. 7. Anlotinib restrains the PI3K/AKT signaling pathway via inhibition of VEGFR2 phosphorylation levels in ICC cells.

Fig. 7

a Western blot assay was used to detect the expression of cell-cycle-related and apoptosis-related proteins and the phosphate expression of VEGFR2 and AKT in ICC cells in different treatment groups; b schematic depiction of the underlying mechanism of anlotinib-inhibiting tumor activity in ICC cells via the VEGFR2/PI3K/AKT signaling pathway.