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. 2020 Jul 9;10(18):8264–8280. doi: 10.7150/thno.45537

Table 4.

Tumor/organ ratios for [177Lu]PentixaTher, [177Lu]DOTA-r-a-ABA-CPCR4 and [177Lu]DOTA-r-a-ABA-iodoCPCR4 in Daudi xenograft bearing CB-17 SCID mice at 48h p.i. (groups of n=4-5 animals). Data are means ± SD.

[177Lu]PentixaTher [177Lu]DOTA-r-a-ABA-CPCR4 [177Lu]DOTA-r-a-ABA-iodoCPCR4
t/blood 201 ± 27 949 ± 146 320 ± 104
t/heart 31 ± 4 111 ± 20 42 ± 7
t/lung 16 ± 5 47 ± 22 14 ± 2
t/liver 0.4 ± 0.1 1.0 ± 0.2 0.6 ± 0.1
t/spleen 2.1 ± 0.5 8.3 ± 2.8 3.0 ± 0.7
t/stomach 27 ± 6 46 ± 32 58 ± 12
t/small intestine 29 ± 6 55 ± 36 50 ± 20
t/colon 13 ± 5 20 ± 10 19 ± 13
t/kidney 2.7 ± 0.4 2.9 ± 0.4 3.1 ± 0.9
t/muscle 85 ± 15 413 ± 100 226 ± 36