Table 6.
Binary Logistic Regression Analysis for Factors Predictive of COVID-19 Severity
Variables | B | SE | p-value | 95% CI | |
---|---|---|---|---|---|
Age | 0.071 | 0.028 | 0.11 | 1.01 | 1.13 |
Sex | 0.56 | 0.55 | 0.315 | 0.58 | 5.2 |
BMI | − 0.14 | 0.099 | 0.138 | 0.71 | 1.04 |
Smoking | − 0.27 | 0.52 | 0.6 | 0.26 | 2.1 |
Co-morbidities | |||||
|
1.6 | 0.74 | 0.032 | 1.14 | 21.5 |
|
1.18 | 0.7 | 0.093 | 0.82 | 12.9 |
|
− 20.5 | 40,192 | 1.0 | 0.0 | — |
Fever | 1.03 | 0.85 | 0.230 | 0.52 | 15.04 |
Cough | 0.24 | 0.49 | 0.621 | 0.48 | 3.37 |
Dyspnea | 1.6 | 0.56 | 0.004 | 1.64 | 15.2 |
Sore throat | 0.96 | 0.53 | 0.069 | 0.92 | 7.4 |
Malaise | 0.69 | 0.53 | 0.196 | 0.7 | 5.7 |
Diarrhea | − 21.04 | 40,192 | 1.0 | 0.0 | — |
Headache | 0.56 | 0.55 | 0.315 | 0.58 | 5.2 |
Hemoglobin (g/dL) | − 0.102 | 0.231 | 0.66 | 0.57 | 1.4 |
WBC (x103 mm−3) | − 0.130 | 0.136 | 0.338 | 0.67 | 1.14 |
Lymphocytic count (x103 mm−3) | − 0.002 | 0.001 | 0.014 | 0.99 | 1.0 |
CRP (mg/dL) | 0.085 | 0.022 | < 0.001 | 1.04 | 1.13 |
ESR (mm/h) | 0.056 | 0.014 | < 0.001 | 1.03 | 1.08 |
Ferritin (ng/mL) | 0.023 | 0.005 | < 0.001 | 1.01 | 1.03 |
Serum creatinine (mg/dL) | 2.09 | 1.47 | 0.156 | 0.44 | 148.03 |
Albumin (g/dL) | − 9.9 | 1.89 | < 0.001 | 0.0 | 0.002 |
ALT (IU/L) | 0.159 | 0.045 | < 0.001 | 1.07 | 1.28 |
AST (IU/L) | 0.75 | 0.2 | < 0.001 | 1.42 | 31.9 |
CT Chest findings | 4.9 | 0.94 | < 0.001 | 0.001 | 0.04 |
Abbreviations: COVID-19, coronavirus disease-2019; B, regression coefficient; SE, standard error; CI, confidence interval; BMI, body mass index; WBC, white blood cell count; CRP, C-reactive protein; ESR, erythrocyte sedimentation rate; ALT, alanine aminotransferase; AST, aspartate aminotransferase; CT, computed tomography.