Table 3.
The Performance of the ANN Model and Scoring Systems in Diagnosing LC in the Training Set and Validation Set
Scoring Systems | Training Set | Validation Set | ||||
---|---|---|---|---|---|---|
AUC | 95% CI | P value | AUC | 95% CI | P value | |
CP score | 0.532 | 0.493–0.571 | 0.103 | 0.538 | 0.470–0.605 | 0.269 |
MELD score | 0.594 | 0.556–0.631 | < 0.001 | 0.544 | 0.477–0.612 | 0.197 |
ALBI score | 0.575 | 0.536–0.613 | < 0.001 | 0.512 | 0.445–0.579 | 0.723 |
APRI score | 0.621 | 0.584–0.658 | < 0.001 | 0.603 | 0.537–0.668 | 0.003 |
FIB-4 score | 0.644 | 0.608–0.681 | < 0.001 | 0.582 | 0.516–0.648 | 0.017 |
AAR score | 0.491 | 0.452–0.530 | 0.638 | 0.470 | 0.403–0.537 | 0.384 |
GPR score | 0.604 | 0.567–0.642 | < 0.001 | 0.623 | 0.559–0.688 | < 0.001 |
ANN model | 0.757 | 0.726–0.788 | < 0.001 | 0.767 | 0.713–0.820 | < 0.001 |
Abbreviations: ANN, artificial neural network; LC, liver cirrhosis; CP, Child-Pugh; MELD, model for end-stage liver disease; ALBI, albumin-bilirubin; APRI, aspartate aminotransferase to platelet ratio index; FIB-4, fibrosis index based on the 4 factor; AAR, aspartate aminotransferase to alanine aminotransferase ratio; GPR, gamma-glutamyl transpeptidase to platelet ratio.