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. 2020 Jul 17;16:639–649. doi: 10.2147/TCRM.S257218

Table 3.

The Performance of the ANN Model and Scoring Systems in Diagnosing LC in the Training Set and Validation Set

Scoring Systems Training Set Validation Set
AUC 95% CI P value AUC 95% CI P value
CP score 0.532 0.493–0.571 0.103 0.538 0.470–0.605 0.269
MELD score 0.594 0.556–0.631 < 0.001 0.544 0.477–0.612 0.197
ALBI score 0.575 0.536–0.613 < 0.001 0.512 0.445–0.579 0.723
APRI score 0.621 0.584–0.658 < 0.001 0.603 0.537–0.668 0.003
FIB-4 score 0.644 0.608–0.681 < 0.001 0.582 0.516–0.648 0.017
AAR score 0.491 0.452–0.530 0.638 0.470 0.403–0.537 0.384
GPR score 0.604 0.567–0.642 < 0.001 0.623 0.559–0.688 < 0.001
ANN model 0.757 0.726–0.788 < 0.001 0.767 0.713–0.820 < 0.001

Abbreviations: ANN, artificial neural network; LC, liver cirrhosis; CP, Child-Pugh; MELD, model for end-stage liver disease; ALBI, albumin-bilirubin; APRI, aspartate aminotransferase to platelet ratio index; FIB-4, fibrosis index based on the 4 factor; AAR, aspartate aminotransferase to alanine aminotransferase ratio; GPR, gamma-glutamyl transpeptidase to platelet ratio.