Table 3.
List of differentially expressed whole-blood immune genes between LF and HF steers
| Gene symbol | Gene name | Fold change1 | P-value |
|---|---|---|---|
| IRF3 | Interferon regulatory factor 3 | 1.35 | <0.01 |
| TLR3 | Toll-like receptor 3 | 1.40 | 0.01 |
| CCR4 | Chemokine (C–C motif) receptor 4 | 1.49 | 0.01 |
| MAPK3 | Mitogen-activated protein kinase 3 | 1.19 | 0.01 |
| TYK2 | Tyrosine kinase 2 | 1.30 | 0.03 |
| STAT3 | Signal transducer and activator of transcription 3 | 1.23 | 0.04 |
| STAT4 | Signal transducer and activator of transcription 4 | 1.35 | 0.02 |
| STAT6 | Signal transducer and activator of transcription 6 | 1.20 | 0.05 |
| CCR8 | Chemokine (C–C motif) receptor 8 | 1.90 | 0.03 |
| GATA3 | GATA binding protein 3 | 1.31 | 0.05 |
| IL2 | Interleukin 2 | 0.51 | 0.02 |
LF = beef steers with lowest average daily gain; HF = beef steers with highest average daily gain.
1Fold change (relative to control) = 2−ΔΔCt = [(CTgene of interest – CTreference genes)HF – (CTgene of interest – CTreference genes)LF]. Only genes with both fold change ≥1.2 or ≤0.83, relative to LF, and P ≤ 0.05 are shown.