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. 2020 Jul 25;1(6):100090. doi: 10.1016/j.patter.2020.100090

Table 2.

Compounds that Appear as Hits in Multiple Studies

Drug Touret et al.3 IC50 (μM) Heiser et al.5 IC50 (μM) Riva et al.6 IC50 (μM) Ellinger et al.4 IC50 (μM) Jeon et al.2 IC50 (μM) Mirabelli et al.1 IC50 (μM) Overlap
Remdesivir 1.65 x 0.62 0.76 11.41 0.10 6
Clofazimine x x 0.08 3
Acitretin x x 2
Almitrine x 1.42 2
Gilteritinib 6.76 0.22 2
Hexachlorophene x 0.90 2
Lopinavir 19.11 9.12 2
Mefloquine 14.15 4.33 2
Niclosamide 0.28 0.14 2
Tetrandrine 1.1 3 2
Tioguanine 1.71 0.022 2

If available, the IC50 value calculated in each study is shown. Otherwise, the hit is marked by an “x.” Note that different studies use different assays and cell lines to measure dose response.