Table 3.
Ranked Predictions for Screen Hits Based on L1000 + MACCS Input with p > 0.01
| Broad Pert. ID | Drug | Hit | Prediction Probability |
|---|---|---|---|
| BRD-K23478508 | digoxin | 1 | 0.8677456 |
| BRD-A34806832 | proscillaridin | 1 | 0.61186494 |
| BRD-A68930007 | ouabain | 1 | 0.48673511 |
| BRD-K13514097 | everolimus | 1 | 0.12437698 |
| BRD-K76674262 | omacetaxine mepesuccinate | 1 | 0.03459994 |
| BRD-K88538023 | oxiconazole | 1 | 0.02330089 |
| BRD-A29731977 | 17-hydroxyprogesterone-caproate | 1 | 0.02278362 |
| BRD-K59873006 | digitoxin | 1 | 0.02124448 |
| BRD-K06926592 | tretinoin | 1 | 0.02050656 |
| BRD-A80908310 | cloperastine | 1 | 0.01705306 |
| BRD-K96390176 | calcipotriol | 1 | 0.01589157 |
| BRD-K33882852 | ZK-93423 | 1 | 0.01579197 |
| BRD-K90699611 | acitretin | 1 | 0.01383878 |
| BRD-A10070317 | propranolol | 1 | 0.01347796 |
| BRD-A99117172 | hydroxychloroquine | 1 | 0.01282602 |
| BRD-A50287119 | sirolimus | 1 | 0.01201528 |
| BRD-K15409150 | penfluridol | 1 | 0.01139704 |
| BRD-A62025033 | temsirolimus | 1 | 0.011242 |
| BRD-K74501079 | azithromycin | 1 | 0.01123628 |
| BRD-K87909389 | alvocidib | 1 | 0.01096243 |
| BRD-K68392338 | ZK-93426 | 1 | 0.01075777 |
| BRD-K99964838 | bosutinib | 1 | 0.01062753 |
| BRD-A62184259 | cycloheximide | 1 | 0.01058221 |
| BRD-K12184470 | flunarizine | 1 | 0.01058221 |
| BRD-K17561142 | amiodarone | 1 | 0.01029646 |
| BRD-A64290322 | cyclosporin A | 1 | 0.0101906 |
| BRD-K68246049 | TTNPB | 1 | 0.01013295 |
| BRD-A91699651 | chloroquine | 1 | 0.01005631 |