Table 2.
Rates of venous thromboembolism in critically ill patients with coronavirus disease 2019
| Author, country | N | Criteria for imaging | Proportion imaged | Proportion of total n with VTE | Cumulative incidence (95% CI) |
|---|---|---|---|---|---|
| Al-Samkari et al., United States5 | 144 | Clinical suspiciona | Not reported | 7.6% | 4.8%/100 patient-weeks |
| Cui et al., ChinaS14 | 81 | Not reported | Not reported | 25% DVT | Not reported |
| Desborough et al., EnglandS15 | 66 | Clinical suspicion | 29% CTPA 10% DVT scan |
15% VTE 5% “true” VTEb |
Not reported |
| Helms et al., France2 | 150 | Clinical suspicion or increase in D-dimer | 66% | 16.6% PE | Not reported |
| Klok et al., NetherlandsS16,S22 | 184 | Clinical suspicion | Not reported | 7 dS16: 15.2% VTE 14 dS22: 35.3% PE |
7 d: 27% (17–37) 14 d: 49% (41–57) |
| Lodigiani et al., ItalyS17 | 61 | Clinical suspicion | ∼20% | 8.3% VTE | 27.6% |
| Middeldorp et al., NetherlandsS18 | 75 | Clinical suspicionc | Not reported | 28% VTE | 7 d: 15% (8–24) 14 d: 28% (18–39) 21 d: 24% (21–46) |
| Poissy et al., FranceS20 | 107 | Clinical suspicion | 31.8% | 22.4% VTE | PE 15 d: 20.4% (13.1–28.7) |
| Thomas et al., EnglandS19 | 62 | Clinical suspicion | 17.7% | 9.6% VTE | 27% (10–47) |
CI, confidence interval; CTPA, computed tomography pulmonary angiogram; DVT, deep vein thrombosis; PE, pulmonary embolism; VTE, venous thromboembolism.
a
Patients treated for VTE without diagnostic imaging not presented here.
b
“True” VTE excludes segmental/subsegmental PE and line-associated DVT.
c
Thirty-eight patients had DVT screening, patients with asymptomatic VTE are excluded from the table.