Table 1.
Placental pathology in COVID-19 positive mothers.
Study | N | GA | COVID-19 | Histological findings |
||
---|---|---|---|---|---|---|
FVM | Other findings | |||||
1 | Mulvey et al. [7] | 5 | 38w–40w | 0 | Thrombosis, Intrauterine fibrin deposition, Villous stromal-vascular karyorrhexis |
Focal increase in perivillous fibrin chorangiosis, Meconium |
2 | Bargen et al. [8] | 20 | 33w–40w | 0 | Thrombosis, Intrauterine fibrin deposition, Villous stromal-vascular karyorrhexis, |
Focal increase in fibrin, Intervillous thrombus, Focal chorangiosis Meconium, Maternal vascular malperfusion |
3 | Shanes et al. [9] | 16 | 33w–40w | 0 | Fetal vessel-mural fibrin, Clustered avascular villi, Delayed villous maturation, Chorangiosis |
Maternal vascular malperfusion |
16w(IUFD) | Villous edema, Retroplacental hematoma |
N, total number of placentas; GA, weeks of gestation; COVID-19, number of COVID-19-positive neonates; FVM, fetal vascular malperfusion.