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Fluorescence in situ hybridization (FISH) analysis was performed using a dual-color MDM2/CEN 12 probe set to detect gene amplification. MDM2 amplifications (neon green) are frequently detected in well-differentiated liposarcoma. (a) No MDM2 gene amplification is identified by FISH analysis in our patient; (b) amplification of the MDM2 gene in a well-differentiated liposarcoma (fluorescence in situ hybridization, FISH).
