Figure 3. Weighted and Adjusted Cumulative Rates of First Myocardial Infarction, Stroke, and Amputation in the Overall High-Deductible Health Plan (HDHP) Cohort and Control Cohort.

A, Myocardial infarction defined as 3 or more days of hospitalization with a myocardial infarction diagnosis at hospital discharge (adjusted hazard ratio [aHR] for follow-up vs baseline year, 1.02; 95% CI, 0.88-1.17). B, Stroke defined as 3 or more days of hospitalization with stroke diagnosis at hospital discharge (aHR for follow-up vs baseline year, 0.99; 95% CI, 0.81-1.23). C, Amputation defined as based on the presence of billing codes for amputation procedures (aHR for follow-up vs baseline year, 0.95; 95% CI, 0.71-1.27); see Methods section for details. Outcome measures could occur more than once per person. We measured first events per person in both the baseline and follow-up periods, thus “resetting” each person to zero events at the beginning of the follow-up period.