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. 2020 Jul 25;21:333. doi: 10.1186/s12859-020-03655-7

Table 1.

Cox coefficients for the subC-LP or subC-CMS models trained on the AFLAME data. Values of the coefficients are indicated along with 95% confidence intervals and P-values

subC-LP
Component beta [CI 95%] Pbeta gamma [CI 95%] Pgamma
 beta0 −0.79 [−1.12, − 0.45] 4.20E-06
 C1 −1.77 [−6.79, 3.24] 4.90E-01 6.48 [0.73, 12.22] 2.70E-02
 C2 −1.21 [−3.83, 1.41] 3.70E-01 2.56 [−0.43, 5.54] 9.30E-02
 C3 3.49 [−0.44, 7.42] 8.20E-02 −5.94 [−10.35, − 1.53] 8.30E-03
 C4 −0.19 [−4.75, 4.36] 9.30E-01 2.79 [−2.55, 8.13] 3.10E-01
 C5 3.11 [−2.57, 8.78] 2.80E-01 −8.89 [−15.63, − 2.15] 9.70E-03
 C6 0.75 [−2.52, 4.02] 6.50E-01 −3.41 [−7.25, 0.43] 8.20E-02
subC-CMS
Component beta [CI 95%] Pbeta gamma [CI 95%] Pgamma
 beta0 −0.75 [−1.08, − 0.42] 7.90E-06
 CMS1 5.81 [−12.96, 1.35] 1.10E-01 17.18 [6.91, 27.46] 1.00E-03
 CMS2 6.29 [−14.94, 2.36] 1.50E-01 19.15 [6.52, 31.78] 3.00E-03
 CMS3 −3.07 [−9.42, 3.27] 3.40E-01 12.02 [2.86, 21.18] 1.00E-02
CMS4 5.38 [−13.52, 2.76] 2.00E-01 16.79 [4.75, 28.83] 6.30E-03