Fig. 6.

ApoE is associated with vascular amyloid in Tg-FDD mice. a, b WB analysis and quantification of ApoE from the cerebral hemisphere and cerebellum of WT and Tg-FDD mice. Vinculin was used as a loading control. For quantifications, error bars represented ± SEM n = 3, where *p < 0.05 of ***p < 0.001, unpaired Student’s t test. c Double immunofluorescence images of apolipoprotein E (ApoE, green) and Danish amyloid (ADan, red) in WT and Tg-FDD brain sections show a high degree of association of ApoE with vascular amyloid in the Tg-FDD (merge). All are representative images of 9-month-old mice cortex. Scale bar 100 μm