Table 2.
Baseline Characteristics of Patients With Adrenal Adenoma
| DST <1.9 μg/dL | DST = 1.9-5.0 μg/dL | P value | |
| N | 275 | 168 | |
| Age, years; median (range) | 59.5 (20.8-83.9) | 66.1 (29.9-91.2) | <0.001 |
| Women, n (%) | 167 (60.7) | 113 (67.3) | 0.166 |
| DST, μg/dL; median (range) | 1.2 (0.9-1.8) | 2.6 (1.9-4.9) | |
|
ACTH, pg/mL; median (range) Missing |
14.0 (5.0-38.0) 207 |
10.5 (4.9-59.0) 116 |
0.066 |
|
DHEA-S, mcg/dL; median (range) Missing |
57.0 (1.9-538.0) 216 |
36.0 (14.0-223.0) 123 |
0.006 |
|
BMI, kg/m2; median (range) BMI, n (%) 10-18.9 19-25.9 26-29.9 30+ Missing |
32 (15-68) 2 (0.7) 39 (14.2) 63 (22.9) 171 (62.2) 0 |
31 (18-58) 2 (1.2) 35 (21.0) 41 (24.6) 89 (53.3) 1 |
0.041
0.202 |
|
Tumor size
a, mm Median (range) Missing |
17 (3-71) 3 |
26 (5-110) 1 |
<0.001 |
|
Duration of prior medical history, years Median (range) |
21.7 (1.0-42.2) | 22.9 (1.0-40.7) | 0.942 |
|
Smoke or other tobacco use, n(%) Never Former Current Missing |
108 (41.2) 96 (36.6) 58 (22.1) 13 |
56 (36.4) 65 (42.2) 33 (21.4) 14 |
0.502 |
|
You/Others felt you needed to reduce alcohol consumption, n (%) Missing |
17 (6.9) 30 |
11 (7.0) 11 |
0.979 |
|
Elixhauser index
b, sum (median, range) Elixhauser, n (%) 0-1 2-4 5+ |
2 (0-17) 93 (33.8) 113 (41.1) 69 (25.1) |
4 (0-15) 42 (25.0) 64 (38.1) 62 (36.9) |
0.002 0.020 |
Abbreviations: ACTH, adrenocorticotropic hormone; BMI, body mass index; DHEA-S, dehydroepiandrosterone sulfate; DST, 1 mg dexamethasone suppression test.
aLarger diameter (if >1 tumor) on closest image to index date (median days from image to index was 18 days (IQR = 1 day to 87 days prior to index date; range -16 years-9 years after index date).
bElixhauser comorbidity index categorizes comorbidities of patients based on the International Classification of Diseases diagnosis codes; data within 5 years prior to the index date was used for this calculation.