Table 4.
Antiproliferative activity of 18 different EBP samples from 16 regions of South Korea pollen ethanol extracts toward 5 cancer cell lines
| Sample | PC-3 cell | MCF-7 cell | A549 cell | NCI-H727 | AGS cell |
|---|---|---|---|---|---|
| IC50, mg/mL | IC50, mg/mL | IC50, mg/mL | IC50, mg/mL | IC50, mg/mL | |
| BP1 | 6.6 ± 0.32def | 1.5 ± 0.17ab | 15.1 ± 0.14cde | 4.6 ± 0.54bcd | 6.8 ± 0.05c |
| BP2 | 5.2 ± 0.21bcd | 1.4 ± 0.13a | 15.3 ± 0.05cde | 2.7 ± 0.27a | 6.9 ± 0.09c |
| BP3 | 7.0 ± 1.36ef | 12.7 ± 0.55j | > 25 | 6.7 ± 0.79efg | 6.7 ± 0.05c |
| BP4 | 14.4 ± 0.07i | 5.1 ± 0.50fgh | 18.5 ± 2.31ef | 9.6 ± 0.24 h | 6.8 ± 0.04c |
| BP5 | 2.9 ± 0.28a | 3.7 ± 0.24cdef | 8.0 ± 0.33b | 3.2 ± 0.08ab | 3.4 ± 0.09ab |
| BP6 | 9.9 ± 0.61 h | 2.8 ± 0.13abcde | 8.8 ± 0.46b | 3.9 ± 0.05abc | 3.4 ± 0.04ab |
| BP7 | 4.0 ± 0.09abc | 0.9 ± 0.11a | 5.0 ± 0.18a | 4.8 ± 0.29bcd | 2.5 ± 0.15ab |
| BP8 | 2.7 ± 0.29a | 5.9 ± 0.55hi | 13.2 ± 0.59 cd | 5.4 ± 0.22cde | 4.1 ± 0.20b |
| BP9 | 3.8 ± 0.31ab | 3.4 ± 0.51bcdef | 9.1 ± 0.68b | 3.4 ± 0.24ab | 3.4 ± 0.06ab |
| BP10 | 6.5 ± 0.45def | 3.5 ± 0.54cdef | 14.8 ± 0.38cde | 9.2 ± 0.37 h | 6.1 ± 0.59c |
| BP11 | 3.3 ± 0.12ab | 1.9 ± 0.20abc | 12.6 ± 0.38c | 5.2 ± 0.46cde | 2.4 ± 0.16ab |
| BP12 | 3.4 ± 0.19ab | 4.5 ± 0.64efgh | 14.9 ± 1.56cde | 17.7 ± 0.33 k | 8.7 ± 1.64d |
| BP13 | 8.9 ± 0.09gh | 6.8 ± 0.46i | 17.0 ± 0.63def | 10.9 ± 0.17i | 8.0 ± 0.27 cd |
| BP14 | 6.9 ± 0.08def | 3.9 ± 0.40defg | 17.8 ± 0.14ef | 7.1 ± 0.21 fg | 6.1 ± 0.01c |
| BP15 | 8.1 ± 0.33 fg | 5.5 ± 0.93ghi | > 25 | 12.8 ± 0.79j | 6.7 ± 0.13c |
| BP16 | 5.7 ± 0.6719cde | 2.4 ± 0.20abcd | 20.6 ± 1.13f | 11.5 ± 0.40i | 7.2 ± 0.07c |
| BP17 | 4.2 ± 0.18abc | 2.3 ± 0.21abcd | 12.0 ± 0.35c | 6.0 ± 0.57dfe | 6.0 ± 0.20c |
| BP18 | 4.3 ± 0.14abc | 2.3 ± 0.06abcd | 19.9 ± 1.91f | 7.8 ± 0.38 g | 3.7 ± 0.07b |
| CNBP | 3.3 ± 0.18ab | 2.8 ± 0.31abcde | 16.1 ± 0.11cde | 2.8 ± 0.11a | 1.8 ± 0.04a |
| Cisplatin | 0.081 ± 0.0053 | 0.005 ± 0.0022 | 0.022 ± 0.0006 | 0.004 ± 0.0003 | 0.035 ± 0.0015 |
CNBP Chinese bee pollen
Different letter (a-k) in the same row indicate significant difference (p < 0.05)