Table 1.
Characteristics at baseline of VACS Patients enrolled in survey sample and of those with clinically confirmed community acquired pneumonia (confirmed-CAP) within the sample
| VACS Survey Sample | With Confirmed-CAP | |||||||
|---|---|---|---|---|---|---|---|---|
| Total | PWH | Uninfected | P | Total | PWH | Uninfected | P | |
| Demographics | 6824 | 3410 | 3414 | – | 397 | 321 | 76 | – |
| Mean age in years (SD) | 49.8 (9.4) | 49.1 (8.8) | 50.4 (10.0) | < 0.001 | 53.3 | 52.2 | 57.8 | < 0.001 |
| Male Gender | 95% | 97% | 92% | < 0.001 | 97% | 98% | 95% | 0.1 |
| Non-white race | 79% | 81% | 76% | < 0.001 | 86% | 89% | 72% | 0.002 |
| Behaviors | ||||||||
| Tobacco use ever | 75% | 77% | 72% | < 0.001 | 86% | 86% | 88% | 0.3 |
| Hazardous alcohol use | 27% | 26% | 28% | 0.009 | 29% | 29% | 28% | 0.8 |
| IV drug use ever | 25% | 33% | 16% | < 0.001 | 41% | 47% | 16% | < 0.001 |
| Comorbidities | ||||||||
| Diabetes mellitus | 33% | 28% | 38% | < 0.001 | 44% | 41% | 54% | .04 |
| CKD | 12% | 13% | 11% | .07 | 24% | 22% | 28% | 0.4 |
| COPD | 5% | 5% | 5% | .7 | 10% | 9% | 14% | 0.2 |
| HCV | 41% | 53% | 28% | < 0.001 | 58% | 65% | 28% | < 0.001 |
| HIV Parameters | ||||||||
| CD4 ≥ 200 cells/μL | – | 76% | – | – | – | 64% | – | – |
| On antiretroviral treatment | – | 72% | – | – | – | 68% | – | – |
| VL ≤500 RNA copies/mL | – | 50% | – | – | – | 40% | – | – |
| EHR CAP Codes | ||||||||
| Any Inpatient CAP ICD-9 code, n (%) | 549 (8) | 433 (13) | 116 (4) | < 0.001 | – | – | – | – |
| Confirmed-CAP by chart review, n (%) | 397 (6) | 321 (9) | 76 (2) | < 0.001 | – | – | – | – |
Age, at time of VACS survey for VACS survey sample, age at time of CAP for those with confirmed-CAP; hazardous alcohol use, based on AUDIT-C score EGFR; IV intravenous; CKD Chronic kidney disease defined as estimated glomerular filtration rate < 60 ml/min, COPD Chronic obstructive pulmonary disease, HCV Hepatitis C infection based on antibody test results and/or HCV RNA, CD4 CD4 cell count, VL Viral load, EHR Electronic health record