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Nobiletin treatment inhibits mitochondrial activity. (a) TCA‐8113 and CAL‐27 cells were incubated with 100 μmol/L nobiletin for 24 hr in the absence or the presence of 50 μmol/L Sp‐cAMP, and then cytochrome oxidase activity was measured. Data from three independent experiments are shown as mean ± SD. *p < .05 compared to control group. (b) Representative immunofluorescent images of TCA‐8113 and Cal‐27 cells labeled with MitoTracker Green. Images were captured at 200× magnification
