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. Author manuscript; available in PMC: 2020 Jul 25.
Published in final edited form as: Cell Rep. 2020 Jul 7;32(1):107860. doi: 10.1016/j.celrep.2020.107860

Figure 6. STRN4 Is a Potential Oncoprotein in Human Endometrial Cancer.

Figure 6.

(A) STRN4 is highly expressed in human endometrial cancer. The alteration frequency of STRN4 is analyzed through the cBioportal database (https://www.cbioportal.org).

(B) STRN4 expression is examined in a panel of endometrial cancer cell lines by western blotting.

(C) YAP cellular localization is examined in a panel of endometrial cancer cell lines by immunofluorescent staining. Scale bar, 20 μm.

(D) Immunohistochemical staining of STRN4 and YAP were performed in endometrial cancer tissue microarrays, where the indicated regions in the box were shown 2.5 times enlarged. Brown staining indicates positive immunoreactivity. Correlation analyses between STRN4 and YAP in human normal endometrial tissue and endometrial adenocarcinoma samples are shown as tables. Statistical significance was determined by chi-square test. R, correlation coefficient; N, nuclear localization; C, cytoplasmic localization. Scale bar, 100 μm.