Fig. 22.

Analysis of intrinsic disorder propensity of Nsp15. Graphs a–c represent intrinsic disorder profiles of Nsp15 protein of a SARS-CoV-2, b human SARS, and c bat CoV. Colour schemes are similar to given in Fig. 3. d A 1.9 Å resolution structure (PDB ID: 6W01) of Nsp15 of SARS CoV-2 consisting of 207–374 residues is represented in cornflower blue colour. e A 2.60 Å crystal structure (PDB ID: 2H85) of Nsp15 from human SARS CoV (rosy brown colour) where residues 151–157 predicted to be disordered are represented in forest green colour