Supplementary Table 1.
Hospital Admissions per Day in a Week in Pre–COVID-19 and COVID-19 Periods and Interrupted Time Series Analysis by Piecewise Linear Regression on Trend of Average Number of Hospital Admissions per Day in a Week Before and After COVID-19 Outbreak
| Entire Pre–COVID-19 Perioda | Season-Adjusted Pre–COVID-19 Perioda | COVID-19 Perioda | Percentage of Change Between Season-Adjusted Pre–COVID-19 Period and COVID-19 Periodb | P Valueb | Change in Intercept After vs Before Outbreakc,d | P Valued | Slope in COVID-19 Periodc,e | P Valuee | |
|---|---|---|---|---|---|---|---|---|---|
| GI cancers | 53 (50–56) | 57 (50–60) | 46 (45–49) | –19.7 | .005 | –8.80 (–36.98 to 19.39) | .535 | 0.02 (–0.44 to 0.49) | .927 |
| Pancreatic and hepatobiliary cancers | 30 (28–32) | 31 (28–33) | 29 (27–31) | –7.8 | .136 | –22.32 (–39.42 to –5.23) | .011 | 0.34 (0.05–0.62) | .021 |
| Benign pancreaticobiliary disorders | 59 (55–62) | 57 (55–60) | 52 (44–55) | –8.8 | .002 | –70.85 (–97.99 to –43.72) | <.001 | 1.07 (0.63–1.52) | <.001 |
| Diseases of the liver | 45 (43–48) | 49 (45–50) | 41 (37–44) | –16.4 | <.001 | –38.18 (–57.95 to –18.41) | <.001 | 0.51 (0.18–0.83) | .003 |
| Noninfective enteritis and colitis (inflammatory bowel disease) | 8 (7–9) | 8 (7–9) | 5 (5–6) | –37.5 | <.001 | –9.39 (–16.43 to –2.34) | .010 | 0.11 (–0.01 to 0.22) | .071 |
| Nonvariceal and variceal UGIB | 57 (53–61) | 59 (55–63) | 45 (43–47) | –23.9 | <.001 | –28.73 (–54.03 to –3.44) | .027 | 0.23 (–0.19 to 0.64) | .286 |
| All digestive diseases | 252 (243–261) | 261 (248–270) | 216 (204–228) | –17.0 | <.001 | –178.27 (–263.70 to –92.85) | <.001 | 2.27 (0.86–3.68) | .002 |
NOTE. The entire pre–COVID-19 period was from January 2019 week 1 to January 2020 week 3. The season-adjusted pre–COVID-19 period was from January 2019 week 4 to May 2019 week 4. The COVID-19 period was from January 2020 week 4 to May 2020 week 4.
Values are median (interquartile range).
Median number of hospital admissions per day of a week in the same period of the year in pre–COVID-19 and COVID-19 periods were compared by the Wilcoxon signed-rank test.
Values in parentheses are 95% confidence intervals.
Change in intercept estimated the immediate change in number of hospital admissions per day in a week right after the COVID-19 outbreak (ie, January 2020 week 4).
The slope estimated the trend of average number of hospital admissions per day in a week (ie, the increase, or decrease if negative trend) of the number of hospital admissions per day in a week during the study period.