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. 2020 Jul 25;130:109192. doi: 10.1016/j.ejrad.2020.109192

Table 3.

Analysis of FP, FN and TN.

Total Age p-value Sex (Male)
FP (n = 66)
Treated for COVID-19 (A) 25 (37.9) 62.7 (17−86) 15 (60)
Not treated for COVID-19 (B) 14 (21.2) 72.1 (35−91) 0.024 4 (28.6) 0.165
Data unknown (C) 27 (40.9) 56.4 (22−96) 12 (44.4)
A x B 0.310* 0.187*
A x C 0.553* 0.789*
B x C 0.020* 1.000*



FN (n = 43)
 Completely negative CT scan (D) 20 (46.5) 49.8 (23−100) 7 (35)
 Confounding pathologies (E) 16 (37.2) 74.9 (35−88) 0.002 11 (68.7) 0.236
 No confounding pathologies (F) 7 (16.3) 59 (42−86) 4 (57.1)
D x E 0.230* 1.000*
D x F 0.001* 0.280*
E x F 0.856* 1.000*



TN (n = 245)
Completely negative CT scan 138 (56.3) 50.1 (16−94) 48 (34.8 %)
Positive CT scan 107 (43.7) 70.1 (17−97) <0.001 61 (57 %) 0.032
  • ­

    COPD

11 (4.5) 67.6 (48−89) 9 (81.8)
  • ­

    CHF

28 (11.4) 79.9 (47−96) 11 (39.3)
  • ­

    Other interstitial pneumonia

14 (5.7) 66.8 (33−88) 10 (71.4)
  • ­

    Community-acquired pneumonia

28 (11.4) 66.1 (17−90) 12 (42.8)
  • ­

    Cancer

13 (5.3) 64.2 (41−87) 10 (76.9)
  • ­

    Only pleural effusion

9 (3.7) 74.3 (42−97) 7 (77.8)
  • ­

    Other findings

4 (1.6) 58 (40−73) 3 (75)

Note: data are patients with percentages in parentheses. Age is mean ± standard deviation.

Abbreviation: RT-PCR, reversed transcription polymerase chain reaction; FP, false positive; FN, false negative; COPD, chronic obstructive pulmonary disease; CHF, congestive heart failure.

*

Multivariate analysis conducted with Bonferroni Test.