Table 3.

Anatomic Location, Etiology and Frequencies of Thrombi with Diagnostic Imaging

Total visceral Thrombotic Events During Disease Course+	N=153	%(from total VTe)
Portal Vein Branch	N=69**	45
Main Vein	41
Left Vein	24
Right Vein	29
Mesenteric Vein	N=41*	26
Superior vein	36
Inferior vein	5
Splenic Vein	N=26	17
Hepatic	N=2	1
Gonadal	N=12*	8
Righit	5
Left	9
Renal Vein	N=3*	2
Right	3
Left	0
Cavernous Transformation	12	12
Budd‒Chiari	4	4
Description of First Thrombi Diagnosed 1		%(from N=95)
Bland thrombus2	19	20
Tumor Thrombus3	8	8
Tumor occluding vein4	9	9
Unable to Asses5	59	62
Patients with ≥ 2 thromboses on first CT scan	N=29	30
Synchronous thromboses with PDAC diagnosis	N=11	11
Mean VT events per patient (range)	1.6(1–4)

Frequencies of Subsequent Visceral Thromboses by Radiographic Diagnosis
	1st		2nd		3rd		4tn		Total
Vein Location	Thrombosis		Thrombosis		Thrombosis		Thrombosis		Thrombosis
	N=95	%	N	%	N	%	N	%	N	%
Portal Vein	60	63	6	6	3	3			69	70
Mesenteric Vein	16	15	23	21	2	2			41	42
Splenic Vein	10	10	9	9	7	6			26	27
Renal Vein	3	2		1					3	3
Gonadal Vein	5	4	6	3			1	1	12	12
Hepatic Vein	1	1	1	1					2	2
Total Subsequent			45	47	12	13	1	1
Thromboses
Other Thromboses
DVT6			9	8	3	3	2		14	14
PE7			5	5	5	5	2		12	12

^*:Counted as a single thrombosis site

^**:Some patients had more than one portal vein branch thrombosed

^+:Patients had more than one vein thrombosed.

^1:As per radiologist CT scans interpretation

^2:Defined as a filling defect in an otherwise well-opacified vein

^3:Tumor thrombus can be differentiated from bland thrombus through the presence of a contiguous adjacent mass and enhancement of a filling defect.

^4:Thrombi were secondary to tumor occluding vein

^5:Radiographically not sufficient to specify thrombi etiology

^6:Deep vein thrombosis (DVT)

^7:pulmonary embolism (PE)