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Association analysis of sex-matched young-onset (aged < 30 years) GD compared with later-onset (aged ≥ 30 years) GD
| rs3094228 | GD Aged < 30 Years (%) | GD Aged ≥ 30 Years (%) | |
|---|---|---|---|
| Genotype frequency | CC | 16 (13) | 23 (7) |
| CT | 67 (57) | 158 (45) | |
| TT | 35 (30) | 170 (48) | |
| P value | 0.00059 | ||
| Allele frequency | C | 99 (42) | 204 (29) |
| T | 137 (58) | 498 (71) | |
| P value (OR [95% CI]) | 0.00025 (OR 1.76 [1.3-2.4]) |
Abbreviations: CI, confidence interval; GD, Graves disease; OR, odds ratio.
