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. 2020 Jul 4;32(3):256–262. doi: 10.4103/JOCO.JOCO_59_20

Table 6.

The results of the current study and other studies that utilize partial-epithelium removal method and epithelial disruptor instruments

Study Study design Mean K (D) BCVA (logMAR) UCVA (logMAR) CCT (µm) Follow-up (m) Number of patients
Rechichi et al.7 Prospective comparative case series Δ=−3.03 Compared to baseline Δ=−0.05 Compared to baseline Δ=−0.25 Compared to baseline Δ=12 Compared to baseline 12 Daya: 28
Hirji et al.8 Retrospective case seriesa Δ=−0.3 Compared to baseline at 12 months Δ=0.1 Compared to baseline at 12 months Δ=0.1 Compared to baseline at 12 months Not reported 9−12 Daya: 128
Galvis et al.11 Retrospective interventional case series Δ=−0.1 Compared to baseline Δ=−0.04 Compared to baseline Not reported Δ=1 Compared to baseline 69.6 Partial deepithelization* 80 eyes
Hashemi et al.12 Retrospective comparative study More improvement in Conventional Δ=−0.42 P=0.015 More improvement in partial Δ=0.13 P=0.001 Same P>0.05 Less decrease in partial Δ=18 P<0.001 12 Conventional=40 eyes Partial**=40 eyes
Current study RCT Δ=−0.01 Conventional Δ=−0.01 Daya P=0.259 Δ=−0.04 Conventional Δ=−0.02 Daya P=0.937 Δ=−0.1 Conventional Δ=−0.02 Daya P=0.868 Δ=−23 Conventional Δ=−2 Daya P=0.0001 12 Conventional=34 Daya=30

aThis study comprises patients operated with hypotonic and isotonic riboflavin. Only the results of the isotonic riboflavin were noted for comparison, *In this study, partial deepithelization procedure was performed with 4-5 vertical full-thickness stripes, 1-1.5 mm wide with 1 mm distance between them, **In this study, partial method was performed with three or four 1-mm-wide vertical strips, 1 mm apart from the central 7 mm of the cornea, and one horizontal strip from the inferior one-third of the cornea. Mean K: Mean keratometry, D: Diopter, BCVA: Best corrected visual acuity, UCVA: Uncorrected visual acuity, CCT: Central corneal thickness, RCT: Randomized clinical trial, Δ: Difference of changes