Table 6.
The results of the current study and other studies that utilize partial-epithelium removal method and epithelial disruptor instruments
Study | Study design | Mean K (D) | BCVA (logMAR) | UCVA (logMAR) | CCT (µm) | Follow-up (m) | Number of patients |
---|---|---|---|---|---|---|---|
Rechichi et al.7 | Prospective comparative case series | Δ=−3.03 Compared to baseline | Δ=−0.05 Compared to baseline | Δ=−0.25 Compared to baseline | Δ=12 Compared to baseline | 12 | Daya: 28 |
Hirji et al.8 | Retrospective case seriesa | Δ=−0.3 Compared to baseline at 12 months | Δ=0.1 Compared to baseline at 12 months | Δ=0.1 Compared to baseline at 12 months | Not reported | 9−12 | Daya: 128 |
Galvis et al.11 | Retrospective interventional case series | Δ=−0.1 Compared to baseline | Δ=−0.04 Compared to baseline | Not reported | Δ=1 Compared to baseline | 69.6 | Partial deepithelization* 80 eyes |
Hashemi et al.12 | Retrospective comparative study | More improvement in Conventional Δ=−0.42 P=0.015 | More improvement in partial Δ=0.13 P=0.001 | Same P>0.05 | Less decrease in partial Δ=18 P<0.001 | 12 | Conventional=40 eyes Partial**=40 eyes |
Current study | RCT | Δ=−0.01 Conventional Δ=−0.01 Daya P=0.259 | Δ=−0.04 Conventional Δ=−0.02 Daya P=0.937 | Δ=−0.1 Conventional Δ=−0.02 Daya P=0.868 | Δ=−23 Conventional Δ=−2 Daya P=0.0001 | 12 | Conventional=34 Daya=30 |
aThis study comprises patients operated with hypotonic and isotonic riboflavin. Only the results of the isotonic riboflavin were noted for comparison, *In this study, partial deepithelization procedure was performed with 4-5 vertical full-thickness stripes, 1-1.5 mm wide with 1 mm distance between them, **In this study, partial method was performed with three or four 1-mm-wide vertical strips, 1 mm apart from the central 7 mm of the cornea, and one horizontal strip from the inferior one-third of the cornea. Mean K: Mean keratometry, D: Diopter, BCVA: Best corrected visual acuity, UCVA: Uncorrected visual acuity, CCT: Central corneal thickness, RCT: Randomized clinical trial, Δ: Difference of changes