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. 2020 Jul 24;6(8):e590. doi: 10.1097/TXD.0000000000001038

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Copyright © 2020 The Author(s). Transplantation Direct. Published by Wolters Kluwer Health, Inc.

This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.

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FIGURE 3. — Comparison of SPF and non-SPF baboon serum IgM/IgG antibody binding and CDC to PBMCs from GTKO, GTKO/β4GalNT2KO, and TKO pigs. On the y axis, the dotted line represents the cut-off values (IgM 1.2, IgG 1.1, CDC 6.4%) below which there is no binding or CDC. The red lines indicate the mean values (**P < 0.01; ns = not significant). CDC, complement-dependent cytotoxicity; GTKO, α1,3-galactosyltransfearse gene-knockout; PBMCs, peripheral blood mononuclear cells; SPF, specific pathogen-free; TKO, triple-knockout.