Table 3.
Treatment Group (n=30) | Control Group A (n=30) | Control Group B (n=30) | ANOVA P-value |
T vs CA | T vs CB | |||||
---|---|---|---|---|---|---|---|---|---|---|
Mean±SD | Within-Group Effect Sizea | Mean±SD | Within-Group Effect Sizea | Mean±SD | Within-Group Effect Sizea | P-valueb | P-valueb | |||
HAMD-17 | Week 0 | 28.17±5.53 | 27.13±4.62 | 27.40±6.46 | 0.76 | |||||
Week 4 | 17.77±6.03 | −0.67 | 25.33±6.51 | −0.16 | 25.77±6.75 | −0.12 | <0.001 | <0.001 | <0.001 | |
Week 8 | 11.20±6.91 | −0.45 | 21.97±6.95 | −0.24 | 25.30±7.29 | −0.03 | <0.001 | <0.001 | <0.001 | |
Week 12 | 12.53±7.87 | 0.09 | 21.10±7.54 | −0.06 | 27.07±7.00 | 0.12 | <0.001 | <0.001 | <0.001 | |
SDS | Week 0 | 43.20±10.50 | 41.40±10.40 | 43.73±8.98 | 0.64 | |||||
Week 4 | 30.57±6.62 | −0.58 | 36.07±12.92 | −0.22 | 38.80±10.44 | −0.25 | 0.009 | 0.35 | 0.003 | |
Week 8 | 26.13±7.58 | −0.30 | 35.13±8.57 | −0.04 | 38.46±8.16 | −0.02 | <0.001 | <0.001 | <0.001 | |
Week 12 | 28.53±7.22 | 0.16 | 35.17±8.00 | 0.002 | 38.30±8.61 | −0.01 | <0.001 | 0.011 | <0.001 | |
HAMA | Week 0 | 22.33±8.76 | 22.97±9.25 | 24.87±8.42 | 0.51 | |||||
Week 4 | 14.27±6.73 | −0.46 | 21.07±8.90 | −0.10 | 22.43±9.14 | −0.14 | <0.001 | 0.012 | <0.001 | |
Week 8 | 9.27±8.06 | −0.32 | 18.17±8.67 | −0.16 | 22.03±10.10 | −0.02 | <0.001 | <0.001 | <0.001 | |
Week 12 | 10.53±7.53 | −0.08 | 16.80±8.29 | −0.08 | 20.90±8.17 | −0.06 | <0.001 | 0.026 | <0.001 |
Notes: aEffect size by Cohen’s d formula. bP-value by Bonferroni correction.
Abbreviations: HAMD-17, Hamilton Rating Scale for Depression; SDS, Self-Rating Depression Scale; HAMA, Hamilton Rating Scale for Anxiety; T, treatment group; CA, control group A; CB, control group B.