Table 7.

The Pharmacokinetic Parameters of 6-Gingerol (6-G) After the Intragastric Administration of Huangqi Guizhi Wuwu Decoction (HGWD) (Mean ± SD, n=5)

Parameters	Blood		Brain
	Normal Group	Model Group	Normal Group	Model Group
t1/2(min)	81.53±21.68	111.81±58.82	200.14±41.05	203.43±38.11
Tmax(min)	25.00	35.00	25.00	25.00
Cmax(ng/mL)	1638.33±226.86	1179.01±183.50*	619.39±75.06	506.44±98.18
V(L/g)	0.29×10−1±0.74×10−2	0.57×10−1±0.31×10−1	0.16±0.12×10−1	0.16±0.24×10−1
CL(L/min/g)	0.25×10−3±0.29×10−4	0.35×10−3±0.62×10−4*	0.57×10−3±0.11×10−3	0.54×10−3±0.54×10−4
AUC0-t (ng · min/mL)	181,512.7±21,224.04	124,603.40±24,478.73*	57,807.41±16,179.63	65,362.58±8471.59
AUC0-inf (ng · min/mL)	199,404.60±25,065.61	141,867.60±22,157.00*	87,520.56±19,259.47	90,045.81±9498.28
MRT(min)	191.52±12.45	210.69±30.77	338.28±6.73	313.97±10.36*

Note: Compared to the normal group, *p<0.05.