Skip to main content
. 2020 Jul 2;4(8):nzaa113. doi: 10.1093/cdn/nzaa113

FIGURE 2.

FIGURE 2

Concentration changes of HMOs in milk of Se+ and Se− mothers during lactation. (A) Overview of HMO subtype changes in Se+ and Se− mothers during lactation. Acidic HMOs are calculated as LSTc + 6′-sialyllactose + 3′-sialyllactose + LSTa + LSTb + disialyllacto-N-tetraose + disialyl lactose. Nonfucosylated HMOs are calculated as lacto-N-triose + lacto-N-neotetraose + p-lacto-N-neohexaose + lacto-N-neohexaose + lacto-N-tetraose + lacto-N-neooctaose. α-1-2-fucosylated HMOs are calculated as LNDFH I + Blood Group A tetrasaccharide + lactodifucotetraose + 2′-FL + LNFP I. α-1-3/4-fucosylated HMOs are calculated as lacto-N-neodifucohexaose + LNDFH II + difucosyllacto-N-hexaose + 3-fucosyllactose + LNFP II + lacto-N-neofucopentaose + LNFP V. Comparison of dynamic changes of (B) HMO concentrations and (C) neutral HMO subtypes in Se+ and Se− mothers during lactation. All values are means ± SEMs. “a”, “b”, … and “x”, “y” … indicate differences among different time points in Se+ and Se− mothers, respectively. # indicates statistical significance between Se+ and Se− mothers at the same lactation time. P < 0.05 was considered significant. HMO, human milk oligosaccharide; LNDFH, lacto-N-difucohexaose; LNFP, lacto-N-fucopentaose; LST, LS-tetrasaccharide; Se+, secretor; Se−, nonsecretor.