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. 2020 Jul 2;4(8):nzaa113. doi: 10.1093/cdn/nzaa113

FIGURE 3.

FIGURE 3

Dynamic changes of 24 HMOs in milk of Se+ and Se− mothers during lactation. Comparison of dynamic changes of (A) acidic, (B) nonfucosylated, (C) α-1-3/4-fucosylated, and (D) α-1-2-fucosylated HMOs in Se+ and Se− mothers during lactation. Acidic HMOs include LSTc, 6′-SL, 3′-SL, LSTa, LSTb, DSLNT, and DS-L. Nonfucosylated HMOs include LNT2, LNnT, p-LNnH + LNnH, LNT, and LNnO. α-1-3/4-fucosylated HMOs include LNnDFH, LNDFH II, DFLNH, 3-FL, LNFP II, LNnFP, and LNFP V. α-1-2-fucosylated HMOs include LNDFH I, A-Type-6, LDFT, 2′-FL, and LNFP I. All values are means ± SEMs. “a,” “b,” … and “x,” “y,” … indicate differences among different time points in Se+ and Se− mothers, respectively. # indicates statistical significance between Se+ and Se− mothers at the same lactation time. P < 0.05 was considered significant. A-Type-6, Blood Group A tetrasaccharide; DFLNH, difucosyllacto-N-hexaose; DS-L, disialyl lactose; DSLNT, disialyllacto-N-tetraose; HMO, human milk oligosaccharide; LDFT, lactodifucotetraose; LNDFH, lacto-N-difucohexaose; LNFP, lacto-N-fucopentaose; LNnDFH, lacto-N-neodifucohexaose; LNnFP, lacto-N-neofucopentaose; LNnH, lacto-N-neohexaose; LNnO, lacto-N-neooctaose; LNnT, lacto-N-neotetraose; LNT, lacto-N-tetraose; LNT2, lacto-N-triose; LST, LS-tetrasaccharide; p-LNnH, p-lacto-N-neohexaose; Se+, secretor; Se−, nonsecretor; 2′-FL, 2′-fucosyllactose; 3-FL, 3-fucosyllactose; 3′-SL, 3′-sialyllactose; 6′-SL, 6′-sialyllactose.