Table 3.
CTM assessment of individual trial inclusion and exclusion criteria
| Trial ID | Median (range), per pt | Total | Agreement |
Median (range), per pt | Total | Agreement |
Median (range), per pt | Total | Agreement |
Median (range), per pt | Total | Agreement |
||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| No. | % | No. | % | No. | % | No. | % | |||||||||
| Not met inclusion criteria | Not met exclusion criteria | Met inclusion criteria | Met exclusion criteria | |||||||||||||
| 1 | 2 (0–4) | 236 | 233 | 99 | 0 (0–2) | 4 | 3 | 75 | 4 (4–4) | 4 | 4 | 100 | 2 (2–2) | 2 | 2 | 100 |
| 2 | 1 (0–4) | 143 | 138 | 97 | 0 | 0 | 0 | – | 5 (3–8) | 58 | 58 | 100 | 0 | 0 | 0 | – |
| 3 | 3 (1–4) | 243 | 237 | 98 | 0 | 0 | 0 | – | 0 | 0 | 0 | – | 0 | 0 | 0 | – |
| 4 | 1 (0–4) | 130 | 126 | 97 | 0 | 0 | 0 | – | 5 (3–6) | 105 | 104 | 99 | 5 (1–7) | 106 | 105 | 99 |
| 5 | 1 (0–3) | 135 | 124 | 92 | 0 | 0 | 0 | – | 7 (4–9) | 27 | 27 | 100 | 1 (0–1) | 2 | 2 | 100 |
| 6 | 1 (0–2) | 79 | 65 | 82 | 0 (0–2) | 28 | 28 | 100 | 5 (2–6) | 229 | 218 | 95 | 3 (0–7) | 138 | 106 | 77 |
| 7 | 1 (0–3) | 93 | 63 | 68 | 0 (0–1) | 18 | 1 | 6 | 5 (3–7) | 68 | 68 | 100 | 2 (0–4) | 26 | 26 | 100 |
| 8 | 2 (0–5) | 253 | 198 | 78 | 0 | 0 | 0 | – | 5 (5–6) | 32 | 31 | 97 | 1 (1–1) | 6 | 6 | 100 |
| 9 | 1 (0–2) | 56 | 56 | 106 | 0 | 0 | 0 | – | 3 (1–5) | 124 | 124 | 100 | 0 | 0 | 0 | – |
| 10 | 0 (0–3) | 72 | 68 | 94 | 0 | 0 | 0 | – | 5 (2–8) | 253 | 251 | 99 | 1 (0–2) | 51 | 49 | 96 |
| All trials | 1440 | 1308 | 91 | 50 | 32 | 64 | 900 | 900 | 885 | 331 | 296 | 89 | ||||
| Action needed inclusion criteria | Action needed exclusion criteria | Unmet modifiable condition | Consent criteria | |||||||||||||
| 1 | 8 (8–8) | 8 | 7 | 88 | 13 (13–13) | 13 | 11 | 85 | 0 | 0 | 0 | – | 3 (3–3) | 3 | 2 | 67 |
| 2 | 7 (5–10) | 82 | 75 | 91 | 23 (22–23) | 250 | 232 | 93 | 1 (0–1) | 7 | 7 | 100 | 2 (1–2) | 20 | 12 | 60 |
| 3 | 0 | 0 | 0 | – | 0 | 0 | 0 | – | 0 | 0 | 0 | – | 0 | 0 | 0 | – |
| 4 | 2 (1–3) | 47 | 43 | 91 | 23 (22–29) | 531 | 484 | 91 | 0 (0–1) | 3 | 3 | 100 | 4 (4–4) | 88 | 68 | 77 |
| 5 | 16 (15/17) | 63 | 56 | 89 | 18 (17–18) | 70 | 65 | 93 | 2 (2–4) | 10 | 2 | 20 | 2 (1–2) | 6 | 6 | 100 |
| 6 | 18 (13–19) | 874 | 750 | 86 | 52 (29–54) | 2567 | 2258 | 88 | 1 (0–5) | 70 | 66 | 94 | 3 (2–3) | 147 | 92 | 63 |
| 7 | 7 (6–11) | 98 | 83 | 85 | 21 (19–22) | 268 | 245 | 91 | 0 (0–3) | 12 | 12 | 100 | 4 (3–4) | 51 | 38 | 75 |
| 8 | 22 (20–22) | 129 | 110 | 85 | 8 (7–8) | 46 | 43 | 93 | 0 (0–1) | 2 | 1 | 50 | 3 (3–3) | 18 | 17 | 94 |
| 9 | 16 (14–17) | 754 | 674 | 89 | 15 (15–15) | 705 | 701 | 99 | 0 (0–2) | 18 | 18 | 100 | 3 (3–3) | 138 | 137 | 99 |
| 10 | 17 (9–21) | 859 | 731 | 85 | 15 (13–16) | 724 | 652 | 90 | 0 (0–3) | 14 | 14 | 100 | 1 (1–2) | 51 | 49 | 96 |
| All trials | 2914 | 2529 | 87 | 5174 | 4691 | 91 | 136 | 123 | 90 | 522 | 421 | 81 | ||||
Note: Not met criteria assessed for all trials; met, action needed, modifiable, and consent criteria assessed only for CTM eligible trials. All patients classified not eligible for trial 3.
Abbreviations: CTM: clinical trial matching; pt: patient.