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. 2020 Jul 25;10:255. doi: 10.1038/s41398-020-00928-w

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — Shown are the results from Experiment 5, consisting of a new cohort of mice that was given the open field test (OFT) twice, followed by two FSTs. A gap of 7 or 14 days was used for shorter versus longer washout periods, respectively, between OFTs or FSTs. Crossing over of drug groups was the same as in Experiments 2 and 3 (maroon grouping: OFT1 = FST1; green grouping: OFT2 = FST2). Error bars represent mean ± SEM. For bars: **adjusted p < 0.01 versus vehicle (or adjusted p value is explicitly shown for a statistical trend). **p < 0.01 for inverted u-shape.