Table 2.

Correlation of clinico-pathological status and LAG3 expression of single-spot and multi-spot TMA

	LAG3 expression single-spot TMA						LAG3 expression multi-spot TMA
		Negative		Positive		p value		Negative		Positive		p value
Total	421	373	88.6%	48	11.4%		161	140	84.8%	21	15.2%
Sex
Female	42	36	85.7%	6	14.3%	0.424	16	15	93.8%	1	6.3%	0.694
Male	379	337	88.9%	42	11.1%		145	125	86.2%	20	13.8%
Age group
< 65	221	189	85.7%	32	14.3%	0.546	70	65	92.9%	5	7.1%	0.060
> 65	200	179	89.4%	21	10.6%		90	74	82.2%	16	17.8%
pT stage
1	50	41	82.0%	9	18.0%	0.370	47	44	93.6%	3	6.4%	0.061
2	36	31	86.1%	5	13.9%		29	21	72.4%	8	27.6%
3	322	290	90.1%	32	9.9%		82	72	87.8%	10	12.2%
4	11	10	90.9%	1	9.1%		1	1	100.0%	0	0.0%
pN stage
0	161	135	83.9%	26	16.1%	0.018	61	55	90.2%	6	9.8%	0.352
pos	259	237	91.5%	22	8.5%		98	83	85.9%	15	14.1%
Neoadjuvant therapy
No	165	148	89.7%	17	10.3%	0.639	139	121	87.1%	18	12.9%	1.000
Yes	256	225	87.9%	31	12.1%		22	19	86.4%	3	13.6%