Table 3.

Multivariate analysis of clinico-pathological status and LAG3 expression for the entire patients´ cohort analysed on the single-spot TMA

	Significance (p value)	Hazard ratio	95% confidence interval
			Lower	Upper
Sex (female vs. male)	0.023	1.742	1.081	2.808
Age group (< 65 vs > 65 years)	0.212	1.149	0.924	1.428
pT (pT1/2 vs pT3/4)	0.018	1.501	1.072	2.100
pN (pN0 vs pN +)	< 0.001	2.804	2.103	3.739
LAG3 (pos. vs neg.)	0.312	0.837	0.593	1.182