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. 2020 Jul 25;20:223. doi: 10.1186/s12866-020-01912-6

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 4 — Intergenic SNV in VPCI591. a. Schematic representation of intergenic variations leading to type I and type II configuration with reference to the direction of transcription of the adjacent genes. SNV position is indicated with vertical red arrows. The two-way arrows (D1, D2, D3), show the distance between the SNV and the downstream genes, bent arrows indicate direction of transcription. b. Distribution of non-genic SNVs relative to the distance from the downstream gene (Type I and II) c. The list flanking genes and their relative distance (D2 and D3) from the intergenic SNVs in Type II configuration