. Author manuscript; available in PMC: 2020 Jul 26.

Published in final edited form as: J Am Acad Dermatol. 2009 Mar;60(3):412–418. doi: 10.1016/j.jaad.2008.10.023

Table III.

Thalidomide off-label indications²³ and supporting evidence based on PubMed search (November 28, 2007, search terms: disease name, randomized controlled clinical trial)

Thalidomide, off-label indications
Observational evidence	Randomized controlled clinical trials
Brain neoplasm	Behçet syndrome
Crohn disease (lenalidomide failed trial)	Cachexia caused by HIV
Discoid lupus erythematosus	Graft-versus-host disease
Erosive lichen planus	Mycobacteriosis
Erythema multiforme	Prevention of recurrent aphthous stomatitis (negative)
Prevention of graft-versus-host disease	Recurrent aphthous stomatitis
Subacute cutaneous lupus erythematosus