Table 1.
Clinical and laboratory features of COVID-19, SARS and MERS.
SARS [13,14,46,52] [[53], [54], [55]] |
MERS [15,19] [24,[56], [57], [58]] |
COVID-19 [18,[59], [60], [61], [62], [63], [64], [65], [66]] | |
---|---|---|---|
Demographic and general characteristics | |||
Male | 25%–60% | 65%–83% | 43%–73% |
Health care personnel | 23%–51% | 8.3–13% | 29% |
Infected by medical and health care | 50%–77% | 55.7%–98% | 41% |
Clinical characters | |||
fever | 99%–100% | 40%–98% | 65%–99% |
cough | 29%–100% | 18%–87% | 22%–82% |
Myalgia | 20%–60% | 7%–32% | 11%–44% |
shortness of breath | 20%–60% | 27%–72% | 4%–35% |
dyspnea | 42%–44% | 5%–15% | 17%–40% |
chills | 15%–74% | 7%–87% | 7%–17% |
diarrhea | 10%–50% | 7%–44% | 1%–10% |
vomiting or nausea | 10%–35% | 7%–21% | 1%–13% |
chest pain | 30% | 15% | 2% |
headache | 15%–70% | 5%–13% | 4%–8% |
sore throat | 11%–30% | 4%–11% | 4%–26% |
runny nose | 2%–24% | 4% | 4% |
Laboratory findings | |||
Leukopenia <4 × 109 |
7%–34% | 6%–14% | 17%–25% |
Lymphopenia <1 × 109 |
54%–75% | 35% | 35%–70% |
Thrombocytopenia | 20%–44.8% | 17%–36% | 21% |
Elevated lactate dehydrogenase | 71%–87% | 47%–49% | 40%–98% |
Elevated alanine transaminase | 23%–56% | 11% | 17%–31% |
Elevated aspartate transaminase | 32%–78% | 15%–53% | 30%–37% |
Complications | |||
diabetes | 5%–40% | 28%–87% | 6%–34% |
hypertension | 11%–30% | 22%–34% | 19%–57% |
Chronic lung disease | 1% | 26%–43% | 2%–17% |
heart disease | 8%–10% | 22%–53% | 8%–18% |
Chronic renal insufficiency | 1%–5% | 5%–53% | 1%–8.5% |
smoking | 5%–20% | 13%–23% | 6%–15.6% |
malignant disease | 6% | 2%–23% | 0.5%–7% |
Abnormal chest radiograph | 70%–100% | 87%–100% | 100% |
Treatment received | |||
Critically ill patients | 20%–23% | 53%–89% | 14%–32% |
Mechanical ventilation support | 13%–50% | 70%–78% | 29%–89% |
Mortality rate | 3.6%–30% | 60%–65% | 4%–28% |
SARS, the severe acute respiratory syndrome; MERS, the Middle East respiratory syndrome; COVID-19, 2019 novel coronavirus disease.