TABLE 1.

Key Technical Advances in Nuclear Cardiology

Innovation	Result
Clinical cardiac PET	Improved speed and accuracy, absolute quantification, list-mode acquisition
Cardiocentric SPECT collimators	Increased count sensitivity, improved speed, lower dose
Solid-state detector SPECT	Increased count sensitivity, improved speed, lower dose, list-mode acquisition, multiisotope acquisition
Iterative reconstruction algorithms	Resolution improvement, noise reduction
List-mode acquisition	Integration of ECG and respiratory gating, motion correction, dynamic imaging sequences for kinetic analysis, simultaneous multiisotope SPECT
Motion correction	Improved resolution for analysis of small target regions
Tracer kinetic analysis	Absolute quantification of physiologic and biologic processes (blood flow, metabolic rates)
Hybrid SPECT/CT, PET/CT	Attenuation correction, integration with calcium score and CT-based coronary angiography, morphologic coregistration
Integrated PET/MRI	Integration with morphology, function, and tissue characteristics; simultaneous multiparametric imaging
SiPM DPC PET/CT	Improved resolution, improved speed, lower dose

ECG = electrocardiography; SiPM DPC = solid-state silicon photomultiplier digital photon counting.