TABLE 1.
Surviving mice at endpoint (n) |
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Mouse | Treatment | Activity (kBq) | 7 d | 21 d |
Rag2−/−γC−/− | PBS | 5/5 | 5/5 | |
212Pb-daratumumab | 185 | 5/5 | 5/5 | |
277.5 | 5/5 | 5/5 | ||
370 | 5/5 | 5/5 | ||
212Pb-anti-mCD38 | 185 | 5/5 | 5/5 | |
370 | 4/5* | 3/5* | ||
C57BL/6 | PBS | 5/5 | 5/5 | |
212Pb-anti-mCD38 | 185 | 6/6 | 6/6 | |
370 | 8/8 | 2/8* |
*Some mice did not survive to endpoint.