Table 4.
Genotypic frequencies of NAION patients and controls
| C677T/A1298C | NAION patients (n = 94) | Controls (n = 204) | p value |
|---|---|---|---|
| TT/AA | 17 (18.09%) | 31 (15.20%) | ns |
| TT/AC | 0 | 0 | ns |
| TT/CC | 0 | 0 | ns |
| CT/AC | 20 (21.28%) | 44 (21.57%) | ns |
| CT/CC | 0 | 0 | ns |
| CT/AA | 27 (28.72%) | 45 (22.06%) | ns |
| CC/AC | 18 (19.15%) | 41 (20.10%) | ns |
| CC/CC | 8 (8.51%) | 19 (9.31%) | ns |
| CC/AA | 4 (4.26%) | 23 (11.27%) | 0.0498 |
Values are presented as n (%). The risk allele is indicated in bold. AC, heterozygotes for A1298C including CT and TC subjects; CT, heterozygotes for C677T including CT and TC subjects; NAION, nonarteritic anterior ischemic optic neuropathy; ns, not significant.