Table 2.
Clinical outcomes by Kaplan–Meier analysis and Cox proportional hazard ratio analysis at 2 years.
| Outcomes | 1G-DES | 2G-DES | Log-rank | Hazard ratio (95% CI) | p value |
|---|---|---|---|---|---|
| All patients | |||||
| POCOs | 100 (13.9) | 353 (8.8) | <0.001 | 1.616 (1.294–2.017) | <0.001 |
| All-cause death | 43 (5.9) | 171 (4.2) | 0.035 | 1.431 (1.024–1.999) | 0.036 |
| Cardiac death | 34 (4.7) | 129 (3.1) | 0.030 | 1.514 (1.037–2.209) | 0.032 |
| Re-MI | 9 (1.3) | 79 (2.0) | 0.192 | 1.576 (0.791–3.141) | 0.196 |
| Death or MI | 52 (7.2) | 244 (6.0) | 0.224 | 1.204 (0.892–1.624) | 0.225 |
| aAny disease revascularization | 58 (8.4) | 138 (3.6) | <0.001 | 2.383 (1.752–3.238) | <0.001 |
| Stent thrombosis (probable or definite) | 14 (1.9) | 28 (0.7) | 0.001 | 2.956 (1.556–5.615) | 0.001 |
| Acute | 1 (0.1) | 2 (0.0) | 0.355 | 2.941 (0.267–32.44) | 0.378 |
| Subacute | 4 (0.6) | 13 (0.3) | 0.290 | 1.814 (0.591–5.563) | 0.298 |
| Late | 7 (1.0) | 10 (0.2) | 0.002 | 4.146 (1.578–10.89) | 0.004 |
| Very late | 2 (0.3) | 3 (0.1) | 0.103 | 3.967 (0.663–23.74) | 0.131 |
|
| |||||
| Propensity score-matched patients | |||||
| POCOs | 94 (13.5) | 64 (9.5) | 0.017 | 1.467 (1.068–2.015) | 0.018 |
| All-cause death | 42 (6.0) | 36 (5.3) | 0.541 | 1.149 (0.736–1.793) | 0.541 |
| Cardiac death | 33 (4.8) | 25 (3.7) | 0.317 | 1.303 (0.775–2.191) | 0.319 |
| Re-MI | 8 (1.2) | 8 (1.2) | 0.971 | 1.019 (0.382–2.714) | 0.971 |
| Death or MI | 50 (7.2) | 44 (6.5) | 0.588 | 1.118 (0.746–1.677) | 0.588 |
| aAny disease revascularization | 54 (8.2) | 24 (3.7) | 0.001 | 2.259 (1.397–3.654) | 0.001 |
| Stent thrombosis (probable or definite) | 13 (1.9) | 3 (0.4) | 0.012 | 4.361 (1.243–15.30) | 0.021 |
| Acute | 1 (0.1) | 0 (0.0) | 0.317 | — | — |
| Subacute | 3 (0.4) | 1 (0.1) | 0.316 | 3.006 (0.313–28.90) | 0.340 |
| Late | 7 (1.0) | 2 (0.3) | 0.093 | 3.526 (0.733–16.98) | 0.116 |
| Very late | 2 (0.3) | 0 (0.0) | 0.155 | — | — |
1G: first-generation; 2G: second-generation; DES: drug-eluting stent; HR: hazard ratio; CI: confidence interval; POCOs: patient-oriented composite outcomes; Re-MI: recurrent myocardial infarction. aAny disease revascularization was composed of target lesion revascularization, target vessel revascularization, and nontarget vessel revascularization.