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. 2020 Jul 18;2020:1710439. doi: 10.1155/2020/1710439

Table 2.

Clinical outcomes by Kaplan–Meier analysis and Cox proportional hazard ratio analysis at 2 years.

Outcomes 1G-DES 2G-DES Log-rank Hazard ratio (95% CI) p value
All patients
POCOs 100 (13.9) 353 (8.8) <0.001 1.616 (1.294–2.017) <0.001
 All-cause death 43 (5.9) 171 (4.2) 0.035 1.431 (1.024–1.999) 0.036
  Cardiac death 34 (4.7) 129 (3.1) 0.030 1.514 (1.037–2.209) 0.032
 Re-MI 9 (1.3) 79 (2.0) 0.192 1.576 (0.791–3.141) 0.196
 Death or MI 52 (7.2) 244 (6.0) 0.224 1.204 (0.892–1.624) 0.225
aAny disease revascularization 58 (8.4) 138 (3.6) <0.001 2.383 (1.752–3.238) <0.001
Stent thrombosis (probable or definite) 14 (1.9) 28 (0.7) 0.001 2.956 (1.556–5.615) 0.001
 Acute 1 (0.1) 2 (0.0) 0.355 2.941 (0.267–32.44) 0.378
 Subacute 4 (0.6) 13 (0.3) 0.290 1.814 (0.591–5.563) 0.298
 Late 7 (1.0) 10 (0.2) 0.002 4.146 (1.578–10.89) 0.004
 Very late 2 (0.3) 3 (0.1) 0.103 3.967 (0.663–23.74) 0.131

Propensity score-matched patients
POCOs 94 (13.5) 64 (9.5) 0.017 1.467 (1.068–2.015) 0.018
 All-cause death 42 (6.0) 36 (5.3) 0.541 1.149 (0.736–1.793) 0.541
  Cardiac death 33 (4.8) 25 (3.7) 0.317 1.303 (0.775–2.191) 0.319
 Re-MI 8 (1.2) 8 (1.2) 0.971 1.019 (0.382–2.714) 0.971
 Death or MI 50 (7.2) 44 (6.5) 0.588 1.118 (0.746–1.677) 0.588
aAny disease revascularization 54 (8.2) 24 (3.7) 0.001 2.259 (1.397–3.654) 0.001
Stent thrombosis (probable or definite) 13 (1.9) 3 (0.4) 0.012 4.361 (1.243–15.30) 0.021
 Acute 1 (0.1) 0 (0.0) 0.317
 Subacute 3 (0.4) 1 (0.1) 0.316 3.006 (0.313–28.90) 0.340
 Late 7 (1.0) 2 (0.3) 0.093 3.526 (0.733–16.98) 0.116
 Very late 2 (0.3) 0 (0.0) 0.155

1G: first-generation; 2G: second-generation; DES: drug-eluting stent; HR: hazard ratio; CI: confidence interval; POCOs: patient-oriented composite outcomes; Re-MI: recurrent myocardial infarction. aAny disease revascularization was composed of target lesion revascularization, target vessel revascularization, and nontarget vessel revascularization.