Table 3.
Cox regression analysis of MACEs in whole, nondiabetic, and diabetic patients.
| Variable | Univariate analysis | Multivariate analysis | ||||
|---|---|---|---|---|---|---|
| Hazard ratio (95% CI) | SEM | P value | Hazard ratio (95% CI) | SEM | P value | |
| Whole | ||||||
| MCV-L | Reference | 0.032 | Reference | 0.032 | ||
| MCV-Mb | 0.899 (0.577-1.401) | 0.226 | 0.638 | 1.159 (0.662-2.028) | 0.286 | 0.606 |
| MCV-Hb | 1.540 (1.038-2.284) | 0.201 | 0.032 | 1.870 (1.113-3.144) | 0.265 | 0.018 |
| Non-DM | ||||||
| MCV-L | Reference | 0.032 | Reference | 0.032 | ||
| MCV-Mb | 1.487 (0.827-2.673) | 0.299 | 0.185 | 1.223 (0.574-2.606) | 0.386 | 0.415 |
| MCV-Hb | 1.963 (1.180-3.265) | 0.260 | 0.009 | 2.089 (1.077-4.501) | 0.338 | 0.029 |
| DM | ||||||
| MCV-L | Reference | 0.328 | ||||
| MCV-Mb | 1.368 (0.695-2.692) | 0.345 | 0.364 | |||
| MCV-Hb | 1.795 (0.816-3.950) | 0.402 | 0.146 | |||
MACEs: major adverse cardiovascular events; MCV: mean corpuscular volume; DM, diabetes mellitus; CI: confidence interval; SEM: standard error of measurement. Adjusted for age, sex, body mass index, smoking, past myocardial infarction, hypertension, creatinine, creatine kinase isoenzymes, pro-B-type natriuretic peptide, and left ventricle ejection fraction. bCompared with MCV-L group.