Table 1.
Baseline characteristics of the SIMD and non-SIMD groups
Characteristics | All patients (n=147) | Patients with SIMD (n=70) | Patients without SIMD (n=77) | P |
Age (year) | 66.0±15.5 | 65.2±14.1 | 66.8±16.6 | 0.592 |
Sex, male | 120 (81.6%) | 57 (81.4%) | 63 (81.8%) | 0.879 |
Treatment day in ICU | 22.3±9.1 | 22.8±9.0 | 21.8±9.1 | 0.285 |
Stroke | 82 (55.8%) | 43 (61.4%) | 39 (51.0%) | 0.251 |
Trauma | 86 (58.5%) | 36 (51.4%) | 50 (64.9%) | 0.136 |
Shock | 50 (34.0%) | 23 (32.9%) | 27 (35.1%) | 0.914 |
COPD | 72 (49.0%) | 43 (61.4%) | 29 (37.7%) | 0.007 |
cTnI (μg/L) | 0.91 (0.13/1.37) | 0.97 (0.22/1.86) | 0.83 (0.08/1.24) | 0.038 |
BNP (pg/mL) | 637.0 (398.5/1010.0) | 678.0 (405.8/1080.0) | 610.0 (347.0/887.5) | 0.267 |
h-FABP (ng/mL) | 9.59 (5.94/12.06) | 11.35 (9.01/14.13) | 8.06 (5.47/10.16) | <0.0005 |
PAPP-A (ng/mL) | 4.49 (2.38/6.61) | 4.57 (2.51/6.71) | 4.44 (2.11/6.44) | 0.359 |
MPO (ng/mL) | 13.96 (10.13/22.99) | 17.62 (11.29/23.38) | 12.11 (8.62/17.23) | 0.011 |
PCT (μg/L) | 3.90 (1.99/5.35) | 3.18 (2.00/5.35) | 3.50 (1.87/5.35) | 0.756 |
APACHE-II score (points) | 19.2±3.0 | 19.4±2.8 | 18.9±3.2 | 0.193 |
SOFA score (points) | 10.3±2.3 | 10.3±2.0 | 10.4±2.5 | 0.871 |
MODS score (points) | 11.4±2.3 | 11.4±2.2 | 11.4±2.5 | 0.825 |
Data are expressed as mean±standard deviation (SD), number (percentage), or median (25th/75th percentile). SIMD: sepsis-induced myocardial dysfunction; ICU: intensive care unit; COPD: chronic obstructive pulmonary disease; cTnI: cardiac troponin I; BNP: brain natriuretic peptide; h-FABP: heart-type fatty acid-binding protein; PAPP-A: pregnancy-associated plasma protein-A; MPO: myeloperoxidase; PCT: procalcitonin; APACHE-II: Acute Physiology and Chronic Health Evaluation II; SOFA: Sequential Organ Failure Assessment; MODS: Multiple Organ Dysfunction Syndrome