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. 2020 Jul 18;2020:3435673. doi: 10.1155/2020/3435673

Table 3.

Multivariate analysis of prognostic factors.

Prognostic factors OS DFS
Hazard ratio (95% CI) P value Hazard ratio (95% CI) P value
Age 1.713 (1.154, 2.543) 0.008 1.474 (1.014, 2.145) 0.042
Tumor location 0.053 0.022
 L 1 1
 M 0.669 (0.392, 1.143) 0.141 0.617 (0.369, 1.032) 0.066
 U 1.526 (0.823, 2.832) 0.180 1.148 (0.630, 2.093) 0.652
 GEJ 1.100 (0.491, 2.465) 0.818 1.192 (0.564, 2.519) 0.645
 Diffuse 1.759 (0.993, 3.118) 0.053 1.919 (1.117, 3.297) 0.018
Tumor size (cm) 1.772 (1.102, 2.849) 0.018 1.556 (0.996, 2.430) 0.052
ypT 0.644 0.438
 0 1 1
 1-2 1.204 (0.138, 10.500) 0.867 1.384 (0.167, 11.434) 0.763
 3-4 1.954 (0.212, 17.971) 0.554 2.340 (0.281, 19.514) 0.432
ypN 0.005 0.011
 0 1 1
 1 5.104 (1.733, 15.027) 0.003 3.317 (1.345, 8.184) 0.009
 2 4.882 (1.618, 14.730) 0.005 3.600 (1.426, 9.088) 0.007
 3 7.641 (2.404, 24.283) 0.001 5.200 (1.949, 13.869) 0.001
ypTNM 0.842 (0.266, 2.663) 0.769 0.747 (0.283, 1.974) 0.557
Histological type 0.934 (0.631, 1.382) 0.731 0.879 (0.605, 1.276) 0.498
Lauren classification 1.433 (0.942, 2.181) 0.093 1.334 (0.900, 1.979) 0.152
Grade of differentiation 1.620 (0.849, 3.093) 0.143 1.666 (0.915, 3.032) 0.095
Vascular or lymphatic invasion 1.739 (1.166, 2.592) 0.007 1.465 (1.002, 2.144) 0.049
Nervous invasion 0.966 (0.645, 1.447) 0.866 0.981 (0.668, 1.441) 0.924
Mandard TRG 1.429 (0.797, 2.561) 0.231 1.430 (0.836, 2.443) 0.191
Adjuvant treatment 2.556 (1.486, 4.396) 0.001 2.556 (1.531, 4.270) 0.001