Table 4.
Multivariate analysis of patients with lymph node metastasis.
| Prognostic factors | OS | DFS | ||
|---|---|---|---|---|
| Hazard ratio (95% CI) | P value | Hazard ratio (95% CI) | P value | |
| Age | 1.815 (1.197, 2.752) | 0.005 | 1.396 (0.932, 2.091) | 0.105 |
| Tumor location | 0.128 | 0.053 | ||
| L | 1 | 1 | ||
| M | 0.626 (0.358, 1.094) | 0.100 | 0.597 (0.342, 1.040) | 0.068 |
| U | 1.196 (0.593, 2.413) | 0.618 | 1.057 (0.532, 2.100) | 0.873 |
| GEJ | 1.139 (0.511, 2.539) | 0.750 | 1.260 (0.599, 2.651) | 0.542 |
| Diffuse | 1.676 (0.932, 3.014) | 0.085 | 1.809 (1.029, 3.012) | 0.040 |
| Tumor size (cm) | 2.093 (1.276, 3.431) | 0.003 | 1.864 (1.153, 3.012) | 0.011 |
| ypT | 0.693 | 0.458 | ||
| 0 | 1 | 1 | ||
| 1-2 | 0.907 (0.098, 8.431) | 0.932 | 1.009 (0.112, 9.109) | 0.994 |
| 3-4 | 0.366 (0.019, 7.221) | 0.509 | 0.280 (0.015, 5.128) | 0.391 |
| ypTNM | 2.432 (0.305, 19.371) | 0.401 | 3.079 (0.424, 22.371) | 0.266 |
| Histological type | 0.913 (0.603, 1.380) | 0.665 | 0.808 (0.539, 1.213) | 0.304 |
| Lauren classification | 1.517 (0.964, 2.389) | 0.072 | 1.431 (0.919, 2.227) | 0.113 |
| Grade of differentiation | 1.360 (0.673, 2.749) | 0.392 | 1.228 (0.630, 2.393) | 0.546 |
| Vascular or lymphatic invasion | 1.903 (1.265, 2.862) | 0.002 | 1.635 (1.101, 2.427) | 0.015 |
| Nervous invasion | 1.003 (0.662, 1.520) | 0.988 | 0.993 (0.662, 1.490) | 0.973 |
| Mandard TRG | 2.034 (1.052, 3.934) | 0.035 | 2.220 (1.162, 4.241) | 0.016 |
| Adjuvant treatment | 2.464 (1.393, 4.358) | 0.002 | 2.339 (1.337, 4.092) | 0.003 |