Table 6.
Performance of the equations according to the range of measured GFR using the threshold of 60 mL/min/1.73 m2.
| eGFRCr (no race adjustment) | eGFRCr (with race adjustment) | eGFRCr-Cys (no race adjustment) | eGFRCr-Cys (with race adjustment) | |
|---|---|---|---|---|
| GFR ≥ 60 mL/min/1.73 m2 (n = 27) | ||||
| Bias (mL/min/1.73 m2) | −4.0 (−11.3–14.6) | 5.5 (−2.6–21.8)a | −3.6 (−11.8–10.2) | 2.4 (−3.8–15.5)b |
| Precision (mL/min/1.73 m2) | 12.1 (8.3–19.7) | 11.6 (4.2–21.8) | 11.0 (5.5–20.0) | 8.7 (3.1–17.3) |
| Accuracy (P30) | 85.2 (66.9–94.7) | 77.8 (58.9–89.7) | 85.2 (66.9–94.7) | 88.9 (71.1–97.0) |
|
| ||||
| GFR < 60 mL/min/1.73 m2 (n = 73) | ||||
| Bias (mL/min/1.73 m2) | 0.1 (−4.9–6.4) | 1.8 (−1.8–7.4)a | 0.1 (−4.1–2.4) | 1.5 (−3.6–3.7)b |
| Precision (mL/min/1.73 m2) | 5.5 (1.6–9.2) | 5.6 (1.8–10.5) | 3.4 (1.7–8.2) | 3.5 (2.2–7.8) |
| Accuracy (P30) | 76.7 (65.7–85.0) | 72.6 (61.4–81.6) | 82.2 (71.7–89.4) | 79.5 (68.7–87.2) |
eGFR: estimated glomerular filtration rate; Cr: creatinine; Cys: cystatin C. Bias and precision are expressed as median (interquartile range), and accuracy as percentage (95% confidence interval). aP < 0.0001 vs. eGFRCr without race adjustment and eGFRCr-Cys without race adjustment; bP < 0.05 vs. eGFRCr-Cys without race adjustment.